Orally active prodrugs of quinoline-4-carboxylic acid angiotensin II receptor antagonists

The discovery of potent nonpeptide angiotensin II receptor antagonists: a new class of potent antihypertensives

John V. Duncia, Andrew T. Chiu, David J. Carini et al. · Journal of Medicinal Chemistry · 1990 · 238 citations · Full text

Hypertension, Medicinal Chemistry, Potent Antihypertensives +15

Routine Direct Measurement of Arterial Pressure in Unanesthetized Rats

Jake Weeks, John A. Jones · Experimental Biology and Medicine · 1960 · 194 citations

Hypertension, Blood Pressure, Vascular Adaptation +15

Antihypertensive activity in rats for SQ 14,225, an orally active inhibitor of angiotensin I-converting enzyme.

Robert J. Laffan, M.E. Goldberg, John P. High et al. · Journal of Pharmacology and Experimental Therapeutics · 1978 · 173 citations

Potent, orally active imidazo[4,5-b]pyridine-based angiotensin II receptor antagonists

Nathan B. Mantlo, Prasun K. Chakravarty, Debra L. Ondeyka et al. · Journal of Medicinal Chemistry · 1991 · 161 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Translational Pharmacology +15

1-(Carboxybenzyl)imidazole-5-acrylic acids: potent and selective angiotensin II receptor antagonists

Joseph Weinstock, Richard M. Keenan, James M. Samanen et al. · Journal of Medicinal Chemistry · 1991 · 127 citations · Full text

Altmetric Attention Score, Pharmacotherapy, Pharmaceutical Chemistry +16