Parker D. Mathers

Dual Metalloprotease Inhibitors:  Mercaptoacetyl-Based Fused Heterocyclic Dipeptide Mimetics as Inhibitors of Angiotensin-Converting Enzyme and Neutral Endopeptidase

Jeffrey A. Robl, Chong‐Qing Sun, Jay Stevenson et al. · Journal of Medicinal Chemistry · 1997 · 198 citations · Full text

Hypertension, Chemical Biology, Medicinal Chemistry +17

Acute γ-Secretase Inhibition of Nonhuman Primate CNS Shifts Amyloid Precursor Protein (APP) Metabolism from Amyloid-β Production to Alternative APP Fragments without Amyloid-β Rebound

Jacquelynn J. Cook, Kristin R. Wildsmith, David B. Gilberto et al. · Journal of Neuroscience · 2010 · 71 citations · Full text

Biphenylsulfonamide Endothelin Antagonists:  Structure−Activity Relationships of a Series of Mono- and Disubstituted Analogues and Pharmacology of the Orally Active Endothelin Antagonist 2‘-Amino-<i>N</i>- (3,4-dimethyl-5-isoxazolyl)-4‘-(2-methylpropyl)[1,1‘-biphenyl]-2-sulfonamide (BMS-187308)

Natesan Murugesan, Zhengxiang Gu, Philip D. Stein et al. · Journal of Medicinal Chemistry · 1998 · 40 citations · Full text

Molecular Pharmacology, Medicinal Chemistry, Pharmaceutical Science +15

CNS Amyloid- , Soluble APP-  and -  Kinetics during BACE Inhibition

Justyna A. Dobrowolska Zakaria, Maria S. Michener, Guoxin Wu et al. · Journal of Neuroscience · 2014 · 39 citations · Full text

Effect of odanacatib on bone turnover markers, bone density and geometry of the spine and hip of ovariectomized monkeys: A head-to-head comparison with alendronate

Donald S. Williams, Paul J. McCracken, Mona Purcell et al. · Bone · 2013 · 37 citations

Bone Turnover Markers, Ovariectomized Monkeys, Bone Health +8