Robert J. Laffan

SQ 14,225 (D-3-mercapto-2-methylpropanoyl-l-proline), a novel orally active inhibitor of angiotensin I-converting enzyme.

Bernard Rubin, Robert J. Laffan, D G Kotler et al. · Journal of Pharmacology and Experimental Therapeutics · 1978 · 210 citations

Molecular Pharmacology, Medicinal Chemistry, Active Inhibitor +13

Antihypertensive activity in rats for SQ 14,225, an orally active inhibitor of angiotensin I-converting enzyme.

Robert J. Laffan, M.E. Goldberg, John P. High et al. · Journal of Pharmacology and Experimental Therapeutics · 1978 · 173 citations

Pharmacology of nadolol (SQ 11725), a β-adrenergic antagonist lacking direct myocardial depression

Robert J. Lee, Dale B. Evans, Sherrin H. Baky et al. · European Journal of Pharmacology · 1975 · 96 citations

Direct Myocardial Depression, Molecular Pharmacology, Medicine +10

EFFECTS OF CHRONIC TREATMENT WITH CAPTOPRIL(SQ 14,225), AN ORALLY ACTIVE INHIBITOR OFANGIOTENSIN I-CONVERTING ENZYME, INSPONTANEOUSLY HYPERTENSIVE RATS

Michael J. Antonaccio, Bernard Rubin, Zola P. Horovitz et al. · The Japanese Journal of Pharmacology · 1979 · 94 citations · Full text

Chronic antihypertensive effects of captopril (SQ 14,225), an orally active angiotensin I-converting enzyme inhibitor, in conscious 2-kidney renal hypertensive rats

Bernard Rubin, Michael J. Antonaccio, Morton E. Goldberg et al. · European Journal of Pharmacology · 1978 · 62 citations

Hypertension, Chronic Antihypertensive Effects, Medicine +7