Enhanced expression of programmed death-1 (PD-1)/PD-L1 in salivary glands of patients with Sjögren's syndrome. - Concepedia

Concepedia

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Enhanced expression of programmed death-1 (PD-1)/PD-L1 in salivary glands of patients with Sjögren's syndrome.

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References

2005

Year

Masaya Kobayashi, Seiji Kawano, Saori Hatachi, Chiyo Kurimoto, Taku Okazaki, Yoshiko Iwai, Tasuku Honjo, Yoshimasa Tanaka, Nagahiro Minato, Takahide Komori,

Abstract

PD-1 is expressed on T lymphocytes and PD-L1 on epithelial cells from inflamed salivary glands of patients with SS, which suggests that dysfunction of the PD-1/PD-L1 pathway may be related to tolerance for lymphocytes, which causes SS.