Concepedia

Publication | Closed Access

Phase I Study of (6R)-5, 10-Dideazatetrahydrofolate: a Folate Antimetabolite Inhibitory to De Novo Purine Synthesis

DOI

70

Citations

0

References

1993

Year

Madhury Ray, Franco M. Muggia, Cynthia G. Leichman, Steven M. Grunberg, R. L. Nelson, Richard W. Dyke, R G Moran
JNCI Journal of the National Cancer Institute

Abstract

Additional phase I studies of DDATHF that relate toxicity to folate intake and tissue folate pools appear warranted.