R G Moran

A new folate antimetabolite, 5,10-dideaza-5,6,7,8-tetrahydrofolate is a potent inhibitor of de novo purine synthesis

G. Peter Beardsley, Barbara A. Moroson, Edward C. Taylor et al. · Journal of Biological Chemistry · 1989 · 230 citations · Full text

Life Sciences, Medicinal Chemistry, Pharmacology +14

Detection of 5-bromodeoxyuridine (BrdUrd) incorporation by monoclonal antibodies: role of the DNA denaturation step.

R G Moran, Zbigniew Darżynkiewicz, Lisa Staiano‐Coico et al. · Journal of Histochemistry & Cytochemistry · 1985 · 136 citations · Full text

Life Sciences, Biochemistry, Molecular Biology +15

Folate metabolism in mammalian cells in culture. I Partial characterization of the folate derivatives present in L1210 mouse leukemia cells.

R G Moran, William C. Werkheiser, Sigmund F. Zakrzewski · Journal of Biological Chemistry · 1976 · 115 citations · Full text

Life Sciences, Biochemistry, Cellular Biochemistry +8

The 6S- and 6R-Diastereomers of 5, 10-Dideaza-5, 6, 7, 8-tetrahydrofolate Are Equiactive Inhibitors of de Novo Purine Synthesis

R G Moran, Samuel Baldwin, Edward C. Taylor et al. · Journal of Biological Chemistry · 1989 · 99 citations · Full text

Medicine, Medicinal Chemistry, Pharmacology +11

Mechanism of the cytotoxic synergism of fluoropyrimidines and folinic acid in mouse leukemic cells.

Khandan Keyomarsi, R G Moran · Journal of Biological Chemistry · 1988 · 97 citations · Full text

Medicine, Oncology, Pharmacology +12