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p21CDKN1A allows the repair of replication-mediated DNA double-strand breaks induced by topoisomerase I and is inactivated by the checkpoint kinase inhibitor 7-hydroxystaurosporine

ChromatinGenome InstabilityCheckpoint Kinase InhibitorNatural SciencesMolecular BiologyDna ReplicationCell CycleTumor SuppressorMedicineCell Biology