An Allosteric Modulator of the α7 Nicotinic Acetylcholine Receptor Possessing Cognition-Enhancing Properties in Vivo

Linkage of a neurophysiological deficit in schizophrenia to a chromosome 15 locus

Robert Freedman, Hilary Coon, Marina Myles‐Worsley et al. · Proceedings of the National Academy of Sciences · 1997 · 1.1K citations

Life Sciences, Genetics, Psychiatry +16

Evidence in postmortem brain tissue for decreased numbers of hippocampal nicotinic receptors in schizophrenia

Robert Freedman, Michael E. Hall, Lawrence E. Adler et al. · Biological Psychiatry · 1995 · 679 citations

Life Sciences, Neurobiology, Neuroscience +11

Diversity of nicotinic acetylcholine receptors in rat hippocampal neurons. I. Pharmacological and functional evidence for distinct structural subtypes.

Manickavasagom Alkondon, Edson X. Albuquerque · Journal of Pharmacology and Experimental Therapeutics · 1993 · 553 citations

Life Sciences, Neuroscience, Pharmacology +17

Proof-of-Concept Trial of an α7 Nicotinic Agonist in Schizophrenia

Ann Olincy, Josette G. Harris, Lynn Johnson et al. · Archives of General Psychiatry · 2006 · 526 citations

Medicine, Neuroscience, Pharmacology +17

Cognitive effects of nicotine

Amir H. Rezvani, Edward D. Levin · Biological Psychiatry · 2001 · 495 citations

Social Sciences, Behavioral Sciences, Psychology +12