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Oxygen consumption is depressed in patients with lactic acidosis due to biguanide intoxication

DOIFull Paper Access

81

Citations

31

References

2010

Year

Alessandro Protti, R Russo, Paola Tagliabue, Sarah Vecchio, Mervyn Singer, Alain Rudiger, Giuseppe Foti, Anna Rossi, Giovanni Mistraletti, Luciano Gattinoni
Critical Care

Abstract

VO2 is abnormally low in patients with lactic acidosis due to biguanide intoxication. This finding is in line with the hypothesis of inhibited mitochondrial respiration and consequent hyperlactatemia.

References

YearCitations

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