Concepedia

Synergistic inhibition of human T-cell lymphotropic virus type III replication in vitro by phosphonoformate and recombinant alpha-A interferon

Kevan L. Hartshorn, E G Sandstrom, DAVID NEUMEYER, Timothy Paradis, Ting‐Chao Chou, Robert T. Schooley, M. S. Hirsch

Antimicrobial Agents and Chemotherapy · 1986 · 64 citations · 19 references

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Abstract

Phosphonoformate and recombinant alpha-A interferon synergistically inhibited the replication of human T-cell lymphotropic virus type III in cultured peripheral blood lymphocytes. T-cell proliferative capability was maintained by this combination, and toxicity was minimal.

References

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Detection, Isolation, and Continuous Production of Cytopathic Retroviruses (HTLV-III) from Patients with AIDS and Pre-AIDS

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David D. Ho, Robert T. Schooley, T R Rota et al. · Science · 1984 · 324 citations

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