Concepedia

Design and synthesis of novel conformationally restricted HIV protease inhibitors

Francesco G. Salituro, Christopher Baker, John J. Court, David D. Deininger, Eunice E. Kim, Biquin Li, Perry M. Novak, B. Govinda Rao, S. Pazhanisamy, Margaret Porter,

Bioorganic & Medicinal Chemistry Letters · 1998 · 37 citations · 7 references

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References

7

Crystal structure of HIV-1 protease in complex with VX-478, a potent and orally bioavailable inhibitor of the enzyme

E. E. Kim, Christopher Baker, M.D. Dwyer et al. · Journal of the American Chemical Society · 1995 · 391 citations

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In vitro selection and characterization of human immunodeficiency virus type 1 (HIV-1) isolates with reduced sensitivity to hydroxyethylamino sulfonamide inhibitors of HIV-1 aspartyl protease

Judith A. Partaledis, Koushi Yamaguchi, Margaret Tisdale et al. · Journal of Virology · 1995 · 186 citations · Full text

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Clinically effective HIV-1 protease inhibitors

Joseph P. Vacca, Jon H. Condra · Drug Discovery Today · 1997 · 110 citations

, , +12

Synthesis of chiral 5-substituted 2-pyrrolidinones: An unusual one-step transformation

Zhong-Yong Wei, Edward E. Knaus · Tetrahedron Letters · 1993 · 37 citations

, , +6

Design, synthesis, and conformational analysis of a novel series of HIV protease inhibitors

Christopher Baker, Francesco G. Salituro, John J. Court et al. · Bioorganic & Medicinal Chemistry Letters · 1998 · 17 citations · Full text

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