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Hypoxic Activation of the PERK/eIF2α Arm of the Unfolded Protein Response Promotes Metastasis through Induction of LAMP3

DOI

121

Citations

48

References

2013

Year

Hilda Mujčić, Anika Nagelkerke, Kasper M.A. Rouschop, Stephen W. Chung, Naz Chaudary, Paul N. Span, Blaise Clarke, Michael Milosevic, Jenna Sykes, Rićhard P. Hill,
Clinical Cancer Research

Abstract

These data suggest that the association between hypoxia, metastasis, and poor prognosis is due, in part, to hypoxic activation of the UPR and expression of LAMP3. Clin Cancer Res; 19(22); 6126-37. ©2013 AACR.

References

YearCitations

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