Concepedia

Protective Effects of the Antiparkinsonian Drugs Talipexole and Pramipexole against 1-Methyl-4-phenylpyridinium-Induced Apoptotic Death in Human Neuroblastoma SH-SY5Y Cells

Yoshihisa Kitamura, Tadashi Kosaka, Jun‐ichi Kakimura, Yasuji Matsuoka, Yasuko Kohno, Yasuyuki Nomura, Takashi Taniguchi

Molecular Pharmacology · 1998 · 181 citations · 35 references

DOI

Concepts

References

35

Chronic Parkinsonism in Humans Due to a Product of Meperidine-Analog Synthesis

J. William Langston, Philip L. Ballard, James W. Tetrud et al. · Science · 1983 · 4.9K citations

, , +14

Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis

Donald W. Nicholson, Ambereen Ali, Nancy A. Thornberry et al. · Nature · 1995 · 4K citations

, , +13

Bcl-2 functions in an antioxidant pathway to prevent apoptosis

David M. Hockenbery, Zoltán N. Oltvai, Xiao-Ming Yin et al. · Cell · 1993 · 3.4K citations

, , +12

Yama/CPP32β, a mammalian homolog of CED-3, is a CrmA-inhibitable protease that cleaves the death substrate poly(ADP-ribose) polymerase

Muneesh Tewari, Long T. Quan, Karen O’Rourke et al. · Cell · 1995 · 2.4K citations · Full text

, , +15

Bcl-2 inhibition of neural death: decreased generation of reactive oxygen species

Darci J. Kane, Theodore A. Sarafian, Rein Anton et al. · Science · 1993 · 1.7K citations

, , +17