Inactivation of <i>HOXA</i> Genes by Hypermethylation in Myeloid and Lymphoid Malignancy is Frequent and Associated with Poor Prognosis - Concepedia

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Inactivation of <i>HOXA</i> Genes by Hypermethylation in Myeloid and Lymphoid Malignancy is Frequent and Associated with Poor Prognosis

DOI Full Paper Access

120

Citations

23

References

2007

Year

Gordon Strathdee, Tessa L. Holyoake, Alyson Sim, Anton Parker, David Oscier, Junia V. Melo, Stefan Meyer, Tim Eden, Anne M. Dickinson, Joanne C. Mountford,

Clinical Cancer Research

Abstract

We propose that in addition to the oncogenic role of some HOX family members, other HOX genes are frequent targets for gene inactivation and normally play suppressor roles in leukemia development.

References

	Year	Citations

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