Tessa L. Holyoake

Guidelines for the use and interpretation of assays for monitoring autophagy

Daniel J. Klionsky, Fábio Camargo Abdalla, Hagai Abeliovich et al. · Autophagy · 2012 · 4K citations · Full text

Mitophagy, Particular Autophagy Assays, Immunology +19

Primitive, quiescent, Philadelphia-positive stem cells from patients with chronic myeloid leukemia are insensitive to STI571 in vitro

Susan M. Graham, Heather G. Jørgensen, Elaine Allan et al. · Blood · 2002 · 1.2K citations · Full text

Dasatinib (BMS-354825) targets an earlier progenitor population than imatinib in primary CML but does not eliminate the quiescent fraction

Mhairi Copland, Ashley Hamilton, Lucy J. Elrick et al. · Blood · 2006 · 631 citations · Full text

Targeting autophagy potentiates tyrosine kinase inhibitor–induced cell death in Philadelphia chromosome–positive cells, including primary CML stem cells

Cristian Bellodi, Maria Rosa Lidonnici, Ashley Hamilton et al. · Journal of Clinical Investigation · 2009 · 556 citations · Full text

Mixed-phenotype Acute Leukemia, Apoptosis, Immunology +21

Targeting mitochondrial oxidative phosphorylation eradicates therapy-resistant chronic myeloid leukemia stem cells

Elodie M. Kuntz, Pablo Baquero, Alison M. Michie et al. · Nature Medicine · 2017 · 543 citations · Full text

Hematological Malignancy, Mitochondrial Function, Medicine +9