Ashley Hamilton

Dasatinib (BMS-354825) targets an earlier progenitor population than imatinib in primary CML but does not eliminate the quiescent fraction

Mhairi Copland, Ashley Hamilton, Lucy J. Elrick et al. · Blood · 2006 · 633 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +5

Targeting autophagy potentiates tyrosine kinase inhibitor–induced cell death in Philadelphia chromosome–positive cells, including primary CML stem cells

Cristian Bellodi, Maria Rosa Lidonnici, Ashley Hamilton et al. · Journal of Clinical Investigation · 2009 · 561 citations · Full text

Life Sciences, Oncology, Cytogenetics +1

Chronic myeloid leukemia stem cells are not dependent on Bcr-Abl kinase activity for their survival

Ashley Hamilton, G. Vignir Helgason, Mirle Schemionek et al. · Blood · 2011 · 429 citations · Full text

Medicine, Hematology, Oncology +14

Epigenetic Reprogramming Sensitizes CML Stem Cells to Combined EZH2 and Tyrosine Kinase Inhibition

Mary T. Scott, Koorosh Korfi, Peter Saffrey et al. · Cancer Discovery · 2016 · 132 citations · Full text

Life Sciences, Molecular Biology, Oncology +17

BMS-214662 potently induces apoptosis of chronic myeloid leukemia stem and progenitor cells and synergizes with tyrosine kinase inhibitors

Mhairi Copland, Francesca Pellicano, Linda Richmond et al. · Blood · 2007 · 117 citations · Full text

Medicine, Oncology, Pharmacology +15