Total Synthesis of the Antibiotic Kendomycin by Macrocyclization using Photo‐Fries Rearrangement and Ring‐Closing Metathesis

Abstract

Crossing swords: Two novel approaches to the antibiotic kendomycin are described. Salient features are complex Claisen–Ireland rearrangements and macrocyclizations by ring-closing metathesis (RCM) and a photo-Fries rearrangement (see retrosynthesis scheme). Detailed facts of importance to specialist readers are published as ”Supporting Information”. Such documents are peer-reviewed, but not copy-edited or typeset. They are made available as submitted by the authors. Please note: The publisher is not responsible for the content or functionality of any supporting information supplied by the authors. Any queries (other than missing content) should be directed to the corresponding author for the article.