Concepedia

Total Synthesis of the Antibiotic Kendomycin by Macrocyclization using Photo‐Fries Rearrangement and Ring‐Closing Metathesis

Thomas Magauer, Harry J. Martin, Johann Mulzer

Angewandte Chemie International Edition · 2009 · 81 citations · 32 references

DOIFull text

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Concepts

Abstract

Crossing swords: Two novel approaches to the antibiotic kendomycin are described. Salient features are complex Claisen–Ireland rearrangements and macrocyclizations by ring-closing metathesis (RCM) and a photo-Fries rearrangement (see retrosynthesis scheme).

References

32

Synthesis and Activity of a New Generation of Ruthenium-Based Olefin Metathesis Catalysts Coordinated with 1,3-Dimesityl-4,5-dihydroimidazol-2-ylidene Ligands

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Synthesis and Applications of RuCl<sub>2</sub>(CHR‘)(PR<sub>3</sub>)<sub>2</sub>:  The Influence of the Alkylidene Moiety on Metathesis Activity

Peter Schwab, Robert H. Grubbs, Joseph W. Ziller · Journal of the American Chemical Society · 1996 · 2.1K citations

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Proton-transfer steps in Steglich esterification: a very practical new method for macrolactonization

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Nozaki−Hiyama−Kishi Reactions Catalytic in Chromium

Alois Fürstner, Nongyuan Shi · Journal of the American Chemical Society · 1996 · 400 citations

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Enantioselective syntheses with titanium carbohydrate complexes. Part 7. Enantioselective allyltitanation of aldehydes with cyclopentadienyldialkoxyallyltitanium complexes

Andreas Hafner, Rudolf O. Duthaler, Roger Martí et al. · Journal of the American Chemical Society · 1992 · 334 citations

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