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Evaluation of alternative solvents in common amide coupling reactions: replacement of dichloromethane and N,N-dimethylformamide

Donna S. Macmillan, Jane Murray, Helen F. Sneddon, Craig Jamieson, Allan J. B. Watson

Green Chemistry · 2012 · 145 citations · 43 references

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Abstract

A range of alternative solvents have been evaluated within amidation reactions employing common coupling reagents with a view to identifying suitable replacements for dichloromethane and N,N-dimethylformamide.

References

43

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