Publication | Closed Access
Expanding GSK's solvent selection guide – embedding sustainability into solvent selection starting at medicinal chemistry
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References
2011
Year
Pharmaceutical SciencePharmaceutical ResearchEngineeringGreen ChemistryPharmaceutical ChemistryMedicinal ChemistryProcess Analytical TechnologyBioanalysisFine ChemicalPharmaceutical TechnologyAnalytical ChemistrySolvent SelectionEnvironmental ImpactChromatographyDrug DevelopmentPharmacologyBiomolecular EngineeringDrug ManufactureEnvironmental EngineeringDrug DiscoveryRational Drug DesignBiotechnologyMedicineActive Pharmaceutical IngredientsAssessment InformationDrug Analysis
Solvents make a large contribution to the environmental impact of manufacturing processes of active pharmaceutical ingredients (API), as well as playing an important role in other chemical industries, with millions of tons used and disposed of each year. GlaxoSmithKline (GSK) has previously reported on the both the development of a GSK solvent selection guide and the incorporation of solvent life cycle inventory and assessment information. The GSK solvent selection guide has been further enhanced by:
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