Concepedia

A Structural Explanation for the Binding of Multiple Ligands by the α-Adaptin Appendage Domain

David J. Owen, Yvonne Vallis, M.E.M. Noble, Jack B. Hunter, Timothy R. Dafforn, Philip R. Evans, Harvey T. McMahon

Cell · 1999 · 285 citations · 44 references

Open access

Concepts

Life SciencesBiochemistryMolecular BiologyStructural BiochemistryStructural BiologyStructural BiophysicsLigand BindingLigand-receptor InteractionsMultivalent InteractionsProtein-ligand BindingProtein-ligand InteractionsReceptor-ligand InteractionsAdaptin SubunitsLigand Binding PathwaysMultivalent LigandsProtein-ligand Binding SitesReceptor-ligand Structural BiologyStructure-based Binding Mechanisms

References

44

The CCP4 suite: programs for protein crystallography

Number Collaborative Computational Project · Acta Crystallographica Section D Biological Crystallography · 1994 · 17.3K citations

Life Sciences, Biochemistry, Biophysics +15

Refinement of Macromolecular Structures by the Maximum-Likelihood Method

Garib N. Murshudov, A. A. Vagin, E. J. Dodson · Acta Crystallographica Section D Biological Crystallography · 1997 · 14.9K citations

Life Sciences, Biochemistry, Biophysics +13

Improved methods for building protein models in electron density maps and the location of errors in these models

T. Alwyn Jones, Jin-yu Zou, Sandra W. Cowan et al. · Acta Crystallographica Section A Foundations of Crystallography · 1991 · 12.7K citations

Life Sciences, Biochemistry, Biomolecular Modeling +16

[27] Maximum-likelihood heavy-atom parameter refinement for multiple isomorphous replacement and multiwavelength anomalous diffraction methods

Eric de La Fortelle, G. Bricogne · Methods in enzymology on CD-ROM/Methods in enzymology · 1997 · 1.9K citations

Natural Sciences, Chemistry, Physics +14

YOLK PROTEIN UPTAKE IN THE OOCYTE OF THE MOSQUITO <i>AEDES AEGYPTI</i>. L

Thomas F. Roth, Keith R. Porter · The Journal of Cell Biology · 1964 · 1.3K citations · Full text

Life Sciences, Cell Biology, Entomology +17