A STAT3-decoy oligonucleotide induces cell death in a human colorectal carcinoma cell line by blocking nuclear transfer of STAT3 and STAT3-bound NF-κB

Stat3 as an Oncogene

Jacqueline Bromberg, Melissa H Wrzeszczynska, Geeta Devgan et al. · Cell · 1999 · 2.8K citations · Full text

Natural Sciences, Reactive Oxygen Specie, Molecular Biology +1

Targeted disruption of the mouse <i>Stat3</i> gene leads to early embryonic lethality

Kiyoshi Takeda, Koichi Noguchi, Wei Shi et al. · Proceedings of the National Academy of Sciences · 1997 · 1.3K citations

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Stattic: A Small-Molecule Inhibitor of STAT3 Activation and Dimerization

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Signaling Pathway, Medicine, Stat3 Activation +5

Leptomycin B Inhibition of Signal-Mediated Nuclear Export by Direct Binding to CRM1

N. Kudo, Barbara Wolff, Toshihiro Sekimoto et al. · Experimental Cell Research · 1998 · 819 citations

Signal Transduction, Signaling Pathway, Cell Regulation +10

Persistently Activated Stat3 Maintains Constitutive NF-κB Activity in Tumors

Heehyoung Lee, Andreas Herrmann, Jiehui Deng et al. · Cancer Cell · 2009 · 685 citations · Full text

Cancer Research, Medicine, Immunology +6