Concepedia

Perforin Triggers a Plasma Membrane-Repair Response that Facilitates CTL Induction of Apoptosis

Dennis Keefe, Lianfa Shi, Stefan Feske, Ramiro Massol, Francisco Navarro, Tomas Kirchhausen, Judy Lieberman

Immunity · 2005 · 313 citations · 35 references

DOIFull text

Open access

Concepts

References

35

Cytotoxicity mediated by T cells and natural killer cells is greatly impaired in perforin-deficient mice

David Kägi, Birgit Ledermann, Kurt Bürki et al. · Nature · 1994 · 1.8K citations

, , +15

Perforin Gene Defects in Familial Hemophagocytic Lymphohistiocytosis

Susan E. Stepp, Rémi Dufourcq-Lagelouse, Françoise Le Deist et al. · Science · 1999 · 1.2K citations

, , +15

Phosphatidylserine-dependent ingestion of apoptotic cells promotes TGF-β1 secretion and the resolution of inflammation

Mai-Lan N. Huynh, Valerie A. Fadok, Peter M. Henson · Journal of Clinical Investigation · 2002 · 1.1K citations · Full text

, , +16

Plasma Membrane Repair Is Mediated by Ca2+-Regulated Exocytosis of Lysosomes

Anita Reddy, Elisabet Caler, Norma W. Andrews · Cell · 2001 · 1K citations · Full text

, , +17

Phosphatidylserine-dependent ingestion of apoptotic cells promotes TGF-β1 secretion and the resolution of inflammation

Mai-Lan N. Huynh, Valerie A. Fadok, Peter M. Henson · Journal of Clinical Investigation · 2002 · 940 citations · Full text

, , +16