Dennis Keefe - Concepedia

Concepedia

Author

Dennis Keefe

Harvard University

Also Known As

D. Keefe, D.A. Keefe, Dennis Keefe, Paul N. Bishop

29

Publications

1.6K

Citations

13

H-Index

37

Concepts

All Affiliations

Harvard University Takeda (United States)Boston Children's Hospital University of Minnesota Friedrich Miescher Institute

DK

About

Dennis Keefe is an author at Harvard University specializing in medicine, cell biology, and cellular physiology.

Top Concepts

#	Concept	H-Index	Publications	Citations
1	Medicine	7	7	1.2K
2	Cell Biology	5	5	819
3	Engineering	2	2	188
4	Biochemistry	2	2	426
5	Social Sciences	1	1	320

Dennis Keefe

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14

Publications

1.6K

Citations

13

H-Index

	Year	Citations
Evidence for neurotransmitter plasticity in vivo: Developmental changes in properties of cholinergic sympathetic neurons Story C. Landis, Dennis Keefe Developmental Biology Synaptic PlasticityDevelopmental BiologyNeurophysiologyDevelopmental ChangesSympathetic Nervous System	1983	320
Perforin Triggers a Plasma Membrane-Repair Response that Facilitates CTL Induction of Apoptosis Dennis Keefe, Lianfa Shi, Stefan Feske, Immunity Signal TransductionCell SignalingApoptosisImmunologyAutophagy	2005	308
Perforin pores in the endosomal membrane trigger the release of endocytosed granzyme B into the cytosol of target cells Jérôme Thiery, Dennis Keefe, Steeve Boulant, Nature Immunology Endocytosed Granzyme BProtein SecretionSignal TransductionBiochemistryTarget Cells	2011	297
The effect of ethylene on the cell-type-specific and intracellular localization of β-1,3-glucanase and chitinase in tobacco leaves Dennis Keefe, Ursula Hinz, Frederick Meins Planta BiosynthesisEngineeringBiochemistryIntracellular LocalizationTobacco Leaves	1990	129
Perforin activates clathrin- and dynamin-dependent endocytosis, which is required for plasma membrane repair and delivery of granzyme B for granzyme-mediated apoptosis Jérôme Thiery, Dennis Keefe, Saviz Saffarian, Blood	2009	126
Granzyme B Binds to Target Cells Mostly by Charge and Must Be Added at the Same Time as Perforin to Trigger Apoptosis Lianfa Shi, Dennis Keefe, Enrique Durand, The Journal of Immunology	2005	83
Anti–sFlt-1 Therapy Preserves Lung Alveolar and Vascular Growth in Antenatal Models of Bronchopulmonary Dysplasia Bradley Wallace, Amelie Peisl, Gregory Seedorf, American Journal of Respiratory and Critical Care Medicine	2017	83
The function of vacuolar β-1,3-glucanase investigated by antisense transformation. Susceptibility of transgenic Nicotiana sylvestris plants to Cercospora nicotianae infection Jean‐Marc Neuhaus, Susan Flores, Dennis Keefe, Plant Molecular Biology Plant ImmunityVacuolar β-1,3-GlucanasePhytoalexinEngineeringFungal Cell Biology	1992	59
Granzyme A, which causes single‐stranded DNA damage, targets the double‐strand break repair protein Ku70 Pengcheng Zhu, Dong Zhang, Dipanjan Chowdhury, EMBO Reports ChromatinGenome InstabilityDna DamageMedicineGenetics	2006	54
Inhibition of FLT1 ameliorates muscular dystrophy phenotype by increased vasculature in a mouse model of Duchenne muscular dystrophy Mayank Verma, Yuko Shimizu‐Motohashi, Yoko Asakura, PLoS Genetics MechanobiologyAngiogenesisDevelopmental BiologyBone Morphogenic ProteinSkeletal Muscle	2019	26

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