Jérôme Thiery

Perforin pores in the endosomal membrane trigger the release of endocytosed granzyme B into the cytosol of target cells

Jérôme Thiery, Dennis Keefe, Steeve Boulant et al. · Nature Immunology · 2011 · 297 citations · Full text

Endocytosed Granzyme B, Protein Secretion, Signal Transduction +10

Capture of MicroRNA–Bound mRNAs Identifies the Tumor Suppressor miR-34a as a Regulator of Growth Factor Signaling

Ashish Lal, Marshall P. Thomas, Gabriel Altschuler et al. · PLoS Genetics · 2011 · 247 citations · Full text

Cytotoxic Cells Kill Intracellular Bacteria through Granulysin-Mediated Delivery of Granzymes

Michael Walch, Farokh Dotiwala, Sachin Mulik et al. · Cell · 2014 · 202 citations · Full text

Granulocyte, Cell Death, Microbiology +4

Perforin activates clathrin- and dynamin-dependent endocytosis, which is required for plasma membrane repair and delivery of granzyme B for granzyme-mediated apoptosis

Jérôme Thiery, Dennis Keefe, Saviz Saffarian et al. · Blood · 2009 · 126 citations · Full text

Melanoma-associated fibroblasts decrease tumor cell susceptibility to NK cell-mediated killing through matrix-metalloproteinases secretion

Linda Ziani, Thouraya Ben Safta-Saadoun, Johanne Gourbeix et al. · Oncotarget · 2017 · 124 citations · Full text

Melanoma-associated Fibroblasts, Promote Tumor Growth, Immunology +17