Concepedia

Generation of platelet-derived microparticles in patients undergoing cardiac surgery is not affected by complement activation

Jeanette M van den Goor, A. van den Brink, Rienk Nieuwland, Willem van Oeveren, P Rutten, Robert Tepaske, Jan G.P. Tijssen, Augueste Sturk, Bas A.J.M. de Mol, L. Eijsman

Journal of Thoracic and Cardiovascular Surgery · 2003 · 17 citations · 27 references

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27

Complement proteins C5b-9 cause release of membrane vesicles from the platelet surface that are enriched in the membrane receptor for coagulation factor Va and express prothrombinase activity.

Peter J. Sims, Elena M. Faioni, Therese Wiedmer et al. · Journal of Biological Chemistry · 1988 · 673 citations · Full text

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Cell-derived Microparticles Circulate in Healthy Humans and Support Low Grade Thrombin Generation

Rienk Nieuwland, Anita N. Böing, Fred P.H.T.M. Romijn et al. · Thrombosis and Haemostasis · 2001 · 642 citations

, , +16

Assembly of the Platelet Prothrombinase Complex Is Linked to Vesiculation of the Platelet Plasma Membrane

Peter J. Sims, Therese Wiedmer, Charles T. Esmon et al. · Journal of Biological Chemistry · 1989 · 598 citations · Full text

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Cellular origin and procoagulant properties of microparticles in meningococcal sepsis

Rienk Nieuwland, R.J. Berckmans, Sarah McGregor et al. · Blood · 2000 · 576 citations

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Sera from patients with heparin-induced thrombocytopenia generate platelet-derived microparticles with procoagulant activity: an explanation for the thrombotic complications of heparin-induced thrombocytopenia

TE Warkentin, L Boshkov, AV Santos et al. · Blood · 1994 · 486 citations · Full text

, , +16