Concepedia

The Toll-like receptor 4 agonist MRP8/14 protein complex is a sensitive indicator for disease activity and predicts relapses in systemic-onset juvenile idiopathic arthritis

Dirk Holzinger, Michael Frosch, Astrid Kastrup, Femke H. M. Prince, M.H. Otten, Lisette W. A. van Suijlekom‐Smit, R. ten Cate, Esther P A H Hoppenreijs, Sandra Hansmann, Halima Moncrieffe,

Annals of the Rheumatic Diseases · 2012 · 163 citations · 25 references

DOIFull text

Open access

Concepts

References

25

International League of Associations for Rheumatology classification of juvenile idiopathic arthritis: second revision, Edmonton, 2001.

Ross E. Petty, T. R. E. Southwood, Prudence Manners et al. · PubMed · 2004 · 4.2K citations · Full text

, , +9

Mrp8 and Mrp14 are endogenous activators of Toll-like receptor 4, promoting lethal, endotoxin-induced shock

Thomas Vogl, Klaus Tenbrock, Stephan Ludwig et al. · Nature Medicine · 2007 · 1.4K citations

, , +16

Preliminary definition of improvement in juvenile arthritis

Edward H. Giannini, Nicolino Ruperto, Angelo Ravelli et al. · Arthritis & Rheumatism · 1997 · 1.1K citations

, , +5

Role of interleukin-1 (IL-1) in the pathogenesis of systemic onset juvenile idiopathic arthritis and clinical response to IL-1 blockade

Virginia Pascual, Florence Allantaz, Edsel Arce et al. · The Journal of Experimental Medicine · 2005 · 917 citations · Full text

, , +17

Development and validation of a composite disease activity score for juvenile idiopathic arthritis

Alessandro Consolaro, Nicolino Ruperto, Anna Bazsó et al. · Arthritis Care & Research · 2009 · 808 citations · Full text

, , +13