Concepedia

Tissue plasminogen activator mediates amyloid‐induced neurotoxicity via Erk1/2 activation

Manel G. Medina, María Dolores Ledesma, Jorge Domínguez, Miguel Medina, Delia Zafra, Francesc Alameda, Carlos G. Dotti, Pilar Navarro

The EMBO Journal · 2005 · 112 citations · 50 references

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Beta-amyloid neurotoxicity requires fibril formation and is inhibited by congo red.

Alfredo Lorenzo, Bruce A. Yankner · Proceedings of the National Academy of Sciences · 1994 · 1.3K citations

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Physiological consequences of loss of plasminogen activator gene function in mice

Peter Carmeliet, Luc Schoonjans, L Kieckens et al. · Nature · 1994 · 1.1K citations

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The proteolytic activity of tissue-plasminogen activator enhances NMDA receptor-mediated signaling

Olivier Nicole, Fabián Docagne, Carine Ali et al. · Nature Medicine · 2001 · 723 citations

, , +16

Linkage of G Protein-Coupled Receptors to the MAPK Signaling Pathway Through PI 3-Kinase γ

Marco López-Ilasaca, Piero Crespo, P. Giuseppe Pellici et al. · Science · 1997 · 674 citations

, , +17

Tissue plasminogen activator (tPA) increase neuronal damage after focal cerebral ischemia in wild-type and tPA-deficient mice

Yanming F. Wang, Stella E. Tsirka, Sidney Strickland et al. · Nature Medicine · 1998 · 630 citations

, , +17