Role of PFKFB3-Driven Glycolysis in Vessel Sprouting

Katrien De Bock, Sandra Schoors, Anna Kuchnio, +39

Cell

Molecular PhysiologyBioengineering ModelPfkfb3-driven GlycolysisVascular BiologyMetabolic Remodeling +4

Single-Cell Transcriptome Atlas of Murine Endothelial Cells

Joanna Kalucka, Laura de Rooij, Jermaine Goveia, +32

Cell

Functional GenomicsSingle Cell SequencingMedicineSingle-cell GenomicsTranscriptomics Technology +5

Physiological consequences of loss of plasminogen activator gene function in mice

Peter Carmeliet, Luc Schoonjans, L Kieckens, +7

Nature

Knockout MouseInduced Pluripotent Stem CellSignal TransductionMolecular PhysiologyCell Signaling +8

A Sertoli cell-selective knockout of the androgen receptor causes spermatogenic arrest in meiosis

Karel De Gendt, Johannes V. Swinnen, Philippa T. K. Saunders, +12

Proceedings of the National Academy of Sciences

Tumour hypoxia causes DNA hypermethylation by reducing TET activity

Bernard Thienpont, Jessica Steinbacher, Hui Zhao, +16

Nature

ChromatinGenome InstabilityNatural SciencesEpigenetic ChangeEpigenomics +6

Fatty acid carbon is essential for dNTP synthesis in endothelial cells

Sandra Schoors, Ulrike Brüning, Rindert Missiaen, +21

Nature

AngiogenesisFatty Acid CarbonBiochemistryEndothelial CellsNatural Sciences +9

Total inactivation of γ–secretase activity in presenilin-deficient embryonic stem cells

An Herreman, Lutgarde Serneels, Wim Annaert, +3

Nature Cell Biology

Embryonic Stem CellDevelopmental BiologyMedicineNatural SciencesNeural Stem Cell +8

An Integrated Gene Expression Landscape Profiling Approach to Identify Lung Tumor Endothelial Cell Heterogeneity and Angiogenic Candidates

Jermaine Goveia, Kateřina Rohlenová, Federico Taverna, +46

Cancer Cell

Functional GenomicsEngineeringTumor HeterogeneityMicroarray Data AnalysisComputational Biology +10

Plasminogen activator inhibitor-1 gene-deficient mice. II. Effects on hemostasis, thrombosis, and thrombolysis.

Peter Carmeliet, J M Stassen, Luc Schoonjans, +5

Journal of Clinical Investigation

ImmunologyPharmacotherapyInflammationThrombosisHematology +15

Plasminogen activator inhibitor-1 gene-deficient mice. I. Generation by homologous recombination and characterization.

Peter Carmeliet, L Kieckens, Luc Schoonjans, +7

Journal of Clinical Investigation

Knockout MouseImmunogeneticsSystems BiologyProtein ExpressionPlasma Pai-1 Levels +10