Bruce A. Yankner

Caspase-12 mediates endoplasmic-reticulum-specific apoptosis and cytotoxicity by amyloid-β

Toshiyuki Nakagawa, Hong Zhu, Nobuhiro Morishima et al. · Nature · 2000 · 3.2K citations

Apoptosis, Cell Death, Degenerative Pathology +5

Neurotrophic and Neurotoxic Effects of Amyloid β Protein: Reversal by Tachykinin Neuropeptides

Bruce A. Yankner, Lawrence K. Duffy, Daniel A. Kirschner · Science · 1990 · 2K citations

Gene regulation and DNA damage in the ageing human brain

Tao Lu, Ying Pan, Shyan-Yuan Kao et al. · Nature · 2004 · 1.9K citations

Lifespan Extension, Dna Damage, Longevity +6

Beta-amyloid neurotoxicity requires fibril formation and is inhibited by congo red.

Alfredo Lorenzo, Bruce A. Yankner · Proceedings of the National Academy of Sciences · 1994 · 1.3K citations · Full text

Neurodegenerative Diseases, Alzheimer's Disease, Medicine +15

APOE4 Causes Widespread Molecular and Cellular Alterations Associated with Alzheimer’s Disease Phenotypes in Human iPSC-Derived Brain Cell Types

Yuan-Ta Lin, Jinsoo Seo, Fan Gao et al. · Neuron · 2018 · 1.1K citations · Full text

Cellular Alterations Associated, Neurodegenerative Diseases, Neurobiology Of Disease +14