Concepedia

Publication | Closed Access

Stimulation of chondrocyte‐mediated cartilage destruction by S100A8 in experimental murine arthritis

DOI

84

Citations

43

References

2008

Year

Peter L. E. M. van Lent, L. Grevers, Arjen B. Blom, Onno J. Arntz, Fons A. J. van de Loo, P. van der Kraan, Shahla Abdollahi‐Roodsaz, Geetha Srikrishna, Hudson H. Freeze, A. Sloëtjes,
Arthritis & Rheumatism

Abstract

These findings indicate that S100A8 and S100A9 are found in and around chondrocytes in experimental arthritis. S100A8 up-regulates and activates MMPs and aggrecanase-mediated pericellular matrix degradation.

References

YearCitations

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