Naringenin inhibits the growth of <i><scp>D</scp>ictyostelium</i> and <scp>MDCK</scp>‐derived cysts in a <scp>TRPP2</scp> (polycystin‐2)‐dependent manner

Abstract

The action of naringenin on cell growth in the phylogenetically diverse systems of Dictyostelium and mammalian kidney cells, suggests a conserved effect mediated by TRPP2 (polycystin-2). Further studies will investigate naringenin as a potential new therapeutic agent in ADPKD.