Marine Drugs · 2004 · 263 citations · 8 references
Natural SciencesMarine SciencesPharmacologyDrug DiscoveryMarine BiodiversityMarine EcologyMarine Bioactive CompoundsMarine BioprospectingMarine Drug DiscoveryMarine Natural ProductsMarine PharmacologyBioactive Marine MetabolitesBioactive Marine Natural ProductsMarine BiodiscoveryMarine Natural Products DiscoveryMarine PharmacognosyMarine-derived Drug DiscoveryNatural Product Chemical DiversitySecondary Metabolites
The marine environment offers a rich source of biological and chemical diversity, yielding unique compounds with potential applications in pharmaceuticals, cosmetics, and other industries, though harnessing this diversity requires multidisciplinary effort. Although only a few marine‑derived products are currently on the market, several robust new compounds are now in the clinical pipeline, with ongoing clinical development.
The marine environment is a rich source of both biological and chemical diversity. This diversity has been the source of unique chemical compounds with the potential for industrial development as pharmaceuticals, cosmetics, nutritional supplements, molecular probes, fine chemicals and agrochemicals. In recent years, a significant number of novel metabolites with potent pharmacological properties has been discovered from the marine organisms. Although there are only a few marine-derived products currently on the market, several robust new compounds derived from marine natural products are now in the clinical pipeline, with more clinical development. While the marine world offers an extremely rich resource for novel compounds, it also represents a great challenge that requires inputs from various scientific areas to bring the marine chemical diversity up to its therapeutic potential.
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Peptide Neurotoxins from Fish-Hunting Cone Snails
Baldomero M. Olivera, William R. Gray, Regina D. Zeikus et al. · Science · 1985 · 748 citations
Biomedical Potential of Marine Natural Products
Brad Carté · BioScience · 1996 · 235 citations · Full text