Concepedia

Differentiation induction enhances bortezomib efficacy and overcomes drug resistance in multiple myeloma

Jingli Gu, Juan Li, Zheng-hai Zhou, Junru Liu, Chang Su

Biochemical and Biophysical Research Communications · 2012 · 28 citations · 27 references

DOI

Concepts

References

27

Cancer Statistics, 2007

Ahmedin Jemal, Rebecca L. Siegel, Elizabeth Ward et al. · CA A Cancer Journal for Clinicians · 2007 · 7.5K citations · Full text

, , +16

Bortezomib or High-Dose Dexamethasone for Relapsed Multiple Myeloma

Paul G. Richardson, Pieter Sonneveld, Michael W. Schuster et al. · New England Journal of Medicine · 2005 · 2.5K citations · Full text

, , +14

Rapid degradation of a large fraction of newly synthesized proteins by proteasomes

Ulrich S. Schubert, Luis C. Antón, James S. Gibbs et al. · Nature · 2000 · 1.5K citations

, , +13

Plasma cell differentiation requires the transcription factor XBP-1

Andreas Reimold, Neal N. Iwakoshi, John Manis et al. · Nature · 2001 · 1.3K citations

, , +12

The proteasome inhibitor bortezomib depletes plasma cells and protects mice with lupus-like disease from nephritis

Kirsten Neubert, Silke Meister, Katrin Moser et al. · Nature Medicine · 2008 · 576 citations

, , +16