Structural alterations of tight junctions are associated with loss of polarity in stroke-prone spontaneously hypertensive rat blood–brain barrier endothelial cells

Occludin: a novel integral membrane protein localizing at tight junctions.

Mikio Furuse, Tetsuaki Hirase, Masahiko Itoh et al. · The Journal of Cell Biology · 1993 · 2.5K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17

Astrocytes induce blood–brain barrier properties in endothelial cells

Robert C. Janzer, Martin Raff · Nature · 1987 · 1.6K citations

Medicine, Cell Biology, Neuroscience +14

The Tight Junction Protein ZO-1 Establishes a Link between the Transmembrane Protein Occludin and the Actin Cytoskeleton

Alan S. Fanning, Brian J. Jameson, Lynne Jesaitis et al. · Journal of Biological Chemistry · 1998 · 1.4K citations · Full text

Life Sciences, Cell Biology, Molecular Biology +13

Claudin multigene family encoding four-transmembrane domain protein components of tight junction strands

Kazumasa Morita, Mikio Furuse, Kazushi Fujimoto et al. · Proceedings of the National Academy of Sciences · 1999 · 1.1K citations

Life Sciences, Cell Biology, Molecular Biology +14

A Single Gene Product, Claudin-1 or -2, Reconstitutes Tight Junction Strands and Recruits Occludin in Fibroblasts

Mikio Furuse, Hiroyuki Sasaki, Kazushi Fujimoto et al. · The Journal of Cell Biology · 1998 · 952 citations · Full text

Life Sciences, Cell Biology, Molecular Biology +17