Concepedia

Progressive, age-related behavioral impairments in transgenic mice carrying both mutant amyloid precursor protein and presenilin-1 transgenes

Gary W. Arendash, David L King, Marcia N. Gordon, D Morgan, Jaime M. Hatcher, Caroline E. Hope, David M. Diamond

Brain Research · 2001 · 350 citations · 27 references

DOI

Concepts

References

27

Correlative Memory Deficits, Aβ Elevation, and Amyloid Plaques in Transgenic Mice

Karen Hsiao, Paul F. Chapman, Steven P. Nilsen et al. · Science · 1996 · 4.2K citations

, , +17

Alzheimer-type neuropathology in transgenic mice overexpressing V717F β-amyloid precursor protein

Dora Games, David S. Adams, Ree Alessandrini et al. · Nature · 1995 · 2.5K citations

, , +16

Memory deficits associated with senescence: A neurophysiological and behavioral study in the rat.

Carol A. Barnes · Journal of Comparative and Physiological Psychology · 1979 · 2.1K citations

, , +17

Mutation of the β-amyloid precursor protein in familial Alzheimer's disease increases β-protein production

Martin Citron, Tilman Oltersdorf, Christian Haass et al. · Nature · 1992 · 1.7K citations

, , +16

Familial Alzheimer's Disease–Linked Presenilin 1 Variants Elevate Aβ1–42/1–40 Ratio In Vitro and In Vivo

David Borchelt, Gopal Thinakaran, Christopher B. Eckman et al. · Neuron · 1996 · 1.5K citations · Full text

, , +17