Publication | Open Access
HLA-A2-Restricted CD8<sup>+</sup>-Cytotoxic-T-Cell Responses to Novel Epitopes in<i>Mycobacterium tuberculosis</i>Superoxide Dismutase, Alanine Dehydrogenase, and Glutamine Synthetase
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Citations
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References
2004
Year
HistocompatibilityMycobacterium Tuberculosis InfectionHla ImmunogeneticsImmunologyAntigen ProcessingCd4 T Cell ResponsesImmune SystemImmunotherapyInflammationProtective Th1 ImmunityNovel EpitopesGlutamine SynthetaseMycobacterial Superoxide DismutaseAutoimmunityT Cell ImmunityCell BiologyPathogenesisHla TypingMicrobiologyAlanine DehydrogenaseCellular Immune ResponseMedicine
Major histocompatibility complex class I-restricted CD8(+) cytotoxic T lymphocytes (CTL) are implicated in protective Th1 immunity to Mycobacterium tuberculosis infection. We report the identification of three novel HLA-A*0201-restricted CTL epitopes within mycobacterial superoxide dismutase (SodA), L-alanine dehydrogenase (AlaDH), and L-glutamine synthetase (GlnS) proteins.
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