Concepedia

Targeting Group II Metabotropic Glutamate (mGlu) Receptors for the Treatment of Psychosis Associated with Alzheimer’s Disease: Selective Activation of mGlu2 Receptors Amplifies β-Amyloid Toxicity in Cultured Neurons, Whereas Dual Activation of mGlu2 and mGlu3 Receptors Is Neuroprotective

Filippo Caraci, Gemma Molinaro, Giuseppe Battaglia, Maria Laura Giuffrida, Barbara Riozzi, Anna Traficante, Valeria Bruno, Milena Cannella, Sara Merlo, Xushan Wang,

Molecular Pharmacology · 2010 · 117 citations · 26 references

References

26

Diffusible, nonfibrillar ligands derived from Aβ <sub>1–42</sub> are potent central nervous system neurotoxins

Mary P. Lambert, Avlin Barlow, Brett A. Chromy et al. · Proceedings of the National Academy of Sciences · 1998 · 3.5K citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Activation of mGlu2/3 receptors as a new approach to treat schizophrenia: a randomized Phase 2 clinical trial

Sandeep T. Patil, Lu Zhang, Ferenc Martényi et al. · Nature Medicine · 2007 · 1K citations

Medicine, Pharmacology, Psychiatry +12

β-Amyloid protein increases the vulnerability of cultured cortical neurons to excitotoxic damage

Jae‐Young Koh, Linda L. Yang, Carl W. Cotman · Brain Research · 1990 · 617 citations

Life Sciences, Neurobiology, Neuroscience +14

β-Amyloid Monomers Are Neuroprotective

Maria Laura Giuffrida, Filippo Caraci, Bruno Pignataro et al. · Journal of Neuroscience · 2009 · 406 citations · Full text

Life Sciences, Neurobiology, Neuroscience +17

Atypical antipsychotic drugs and risk of ischaemic stroke: population based retrospective cohort study

Sudeep S. Gill, Paula A. Rochon, Nathan Herrmann et al. · BMJ · 2005 · 402 citations · Full text

Medicine, Geriatric Medicine, Pharmacotherapy +13