Xushan Wang

Efficacy, Safety, and Immunogenicity of an Enterovirus 71 Vaccine in China

Fengcai Zhu, Wenbo Xu, Jielai Xia et al. · New England Journal of Medicine · 2014 · 458 citations · Full text

Targeting Group II Metabotropic Glutamate (mGlu) Receptors for the Treatment of Psychosis Associated with Alzheimer’s Disease: Selective Activation of mGlu2 Receptors Amplifies β-Amyloid Toxicity in Cultured Neurons, Whereas Dual Activation of mGlu2 and mGlu3 Receptors Is Neuroprotective

Filippo Caraci, Gemma Molinaro, Giuseppe Battaglia et al. · Molecular Pharmacology · 2010 · 115 citations

N-(4-((2-(trifluoromethyl)-3-hydroxy-4-(isobutyryl)phenoxy)methyl)benzyl)-1-methyl-1H-imidazole-4-carboxamide (THIIC), a Novel Metabotropic Glutamate 2 Potentiator with Potential Anxiolytic/Antidepressant Properties: In Vivo Profiling Suggests a Link between Behavioral and Central Nervous System Neurochemical Changes

Matthew Fell, Jeffrey M. Witkin, Julie F. Falcone et al. · Journal of Pharmacology and Experimental Therapeutics · 2010 · 99 citations

Complete Inhibition of Anisomycin and UV Radiation but Not Cytokine Induced JNK and p38 Activation by an Aryl-substituted Dihydropyrrolopyrazole Quinoline and Mixed Lineage Kinase 7 Small Interfering RNA

Xushan Wang, Mary M. Mader, John E. Toth et al. · Journal of Biological Chemistry · 2005 · 87 citations · Full text

Synthesis and Pharmacological Characterization of C4-Disubstituted Analogs of 1<i>S</i>,2<i>S</i>,5<i>R</i>,6<i>S</i>-2-Aminobicyclo[3.1.0]hexane-2,6-dicarboxylate: Identification of a Potent, Selective Metabotropic Glutamate Receptor Agonist and Determination of Agonist-Bound Human mGlu2 and mGlu3 Amino Terminal Domain Structures

James A. Monn, Lourdes Prieto, Lorena Taboada et al. · Journal of Medicinal Chemistry · 2015 · 59 citations

Pharmacological Characterization, Pharmacotherapy, Experimental Pharmacology +18