In Vitro Hepatic Metabolism Explains Higher Clearance of Voriconazole in Children versus Adults: Role of CYP2C19 and Flavin-Containing Monooxygenase 3

Prediction of the Clearance of Eleven Drugs and Associated Variability in Neonates, Infants and Children

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Pharmacokinetic/Pharmacodynamic Profile of Voriconazole

Ursula Theuretzbacher, Franziska Ihle, Hartmut Derendorf · Clinical Pharmacokinetics · 2006 · 475 citations

Medicine, Pharmacokinetics, Pharmacology +12

Pharmacokinetics and Safety of Voriconazole following Intravenous- to Oral-Dose Escalation Regimens

Lynn Purkins, Nolan Wood, Parviz Ghahramani et al. · Antimicrobial Agents and Chemotherapy · 2002 · 413 citations · Full text

Pharmacy, Clinical Pharmacokinetics, Pharmacology +13

Identification of the Cytochrome P450 Enzymes Involved in the N-Oxidation of Voriconazole

Ruth Hyland, B. C. Jones, Dennis A. Smith · Drug Metabolism and Disposition · 2003 · 381 citations

Medicine, Biochemistry, Pharmacology +17

Pharmacokinetics and Safety of Intravenous Voriconazole in Children after Single- or Multiple-Dose Administration

Thomas J. Walsh, Mats O. Karlsson, Timothy Driscoll et al. · Antimicrobial Agents and Chemotherapy · 2004 · 335 citations · Full text

Pharmacy, Pharmacokinetics, Pharmacology +17