Dhiren R. Thakker

Tumorigenicity of the optical enantiomers of the diastereomeric benzo[a]pyrene 7,8-diol-9,10-epoxides in newborn mice: exceptional activity of (+)-7beta,8alpha-dihydroxy-9alpha,10alpha-epoxy-7,8,9,10-tetrahydrobenzo[a]pyrene.

Mildred K. Buening, Peter G. Wislocki, Wayne Levin et al. · Proceedings of the National Academy of Sciences · 1978 · 381 citations · Full text

Medicine, Oncology, Pharmacology +10

Metabolism of benzo[a]pyrene VI. Stereoselective metabolism of benzo[a]pyrene and benzo[a]pyrene 7,8-dihydrodiol to diol epoxides

Dhiren R. Thakker, Haruhiko Yagi, H. Akagi et al. · Chemico-Biological Interactions · 1977 · 262 citations

Medicine, Chemistry, Pharmacology +12

Enhancing paracellular permeability by modulating epithelial tight junctions

Peter Ward, Tim K. Tippin, Dhiren R. Thakker · Pharmaceutical Science & Technology Today · 2000 · 220 citations

Life Sciences, Cell Biology, Physiology +14

Metabolism of benzo[a]pyrene: conversion of (+/-)-trans-7,8-dihydroxy-7,8-dihydrobenzo[a]pyrene to highly mutagenic 7,8-diol-9,10-epoxides.

Dhiren R. Thakker, Haruhiko Yagi, Anthony Y.H. Lu et al. · Proceedings of the National Academy of Sciences · 1976 · 205 citations · Full text

Life Sciences, Biochemistry, Toxicology +15

Evidence for a Polarized Efflux System in Caco-2 Cells Capable of Modulating Cyclosporine A Transport

Patrick Augustijns, T. Bradshaw, Liang Gan et al. · Biochemical and Biophysical Research Communications · 1993 · 172 citations

Life Sciences, Biophysics, Cell Biology +12