Concepedia

Identification of the Cytochrome P450 Enzymes Involved in the N-Oxidation of Voriconazole

Ruth Hyland, B. C. Jones, Dennis A. Smith

Drug Metabolism and Disposition · 2003 · 381 citations · 18 references

DOI

Concepts

References

18

The Carbon Monoxide-binding Pigment of Liver Microsomes

Tsuneo Omura, Ryo Sato · Journal of Biological Chemistry · 1964 · 11.8K citations · Full text

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Interindividual variations in human liver cytochrome P-450 enzymes involved in the oxidation of drugs, carcinogens and toxic chemicals: studies with liver microsomes of 30 Japanese and 30 Caucasians.

Tsutomu Shimada, Hiroshi Yamazaki, Mayumi Mimura et al. · Journal of Pharmacology and Experimental Therapeutics · 1994 · 2.8K citations

, , +15

Cytochrome P450 inhibitors. Evaluation of specificities in the in vitrometabolism of therapeutic agents by human liver microsomes.

Deborah J. Newton, R W Wang, Anthony Y.H. Lu · Drug Metabolism and Disposition · 1995 · 606 citations

, , +17

Cytochrome P 450 isoenzymes, epoxide hydrolase and glutathione transferases in rat and human hepatic and extrahepatic tissues.

Isabelle de Waziers, Paul‐Henri Cugnenc, Chunsong Yang et al. · Journal of Pharmacology and Experimental Therapeutics · 1990 · 502 citations

, , +16

Pharmacokinetics and Safety of Voriconazole following Intravenous- to Oral-Dose Escalation Regimens

Lynn Purkins, Nolan Wood, Parviz Ghahramani et al. · Antimicrobial Agents and Chemotherapy · 2002 · 413 citations · Full text

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