Concepedia

Lipid modification of GRN163, an N3′ → P5′ thio-phosphoramidate oligonucleotide, enhances the potency of telomerase inhibition

Brittney‐Shea Herbert, Ginelle C. Gellert, Amelia E. Hochreiter, Krisztina Pongracz, Woodring E. Wright, Daria Zielińska, Allison C. Chin, Calvin B. Harley, Jerry W. Shay, Sergei Gryaznov

Oncogene · 2005 · 264 citations · 25 references

DOI

Concepts

References

25

Specific Association of Human Telomerase Activity with Immortal Cells and Cancer

Nam W. Kim, Mieczyslaw A. Piatyszek, Karen R. Prowse et al. · Science · 1994 · 7.1K citations

, , +16

Inhibition of telomerase limits the growth of human cancer cells

William C. Hahn, Sheila A. Stewart, Mary W. Brooks et al. · Nature Medicine · 1999 · 1K citations

, , +12

Absence of cancer–associated changes in human fibroblasts immortalized with telomerase

Carmela P. Morales, Shawn E. Holt, Michel M. Ouellette et al. · Nature Genetics · 1999 · 798 citations

, , +14

Telomere shortening and apoptosis in telomerase-inhibited human tumor cells

X. Zhang, V L Mar, Wen Zhou et al. · Genes & Development · 1999 · 699 citations · Full text

, , +16

Advances in quantification and characterization of telomerase activity by the telomeric repeat amplification protocol (TRAP)

Nayoung Kim · Nucleic Acids Research · 1997 · 688 citations

, , +15