Striatal oxidative damage parallels the expression of a neurological phenotype in mice transgenic for the mutation of Huntington’s disease

A novel gene containing a trinucleotide repeat that is expanded and unstable on Huntington's disease chromosomes

Marcy E. MacDonald · Cell · 1993 · 8.4K citations · Full text

Life Sciences, Genetics, Molecular Genetics +13

Exon 1 of the HD Gene with an Expanded CAG Repeat Is Sufficient to Cause a Progressive Neurological Phenotype in Transgenic Mice

Laura Mangiarini, Kirupa Sathasivam, Mary J. Seller et al. · Cell · 1996 · 3.1K citations · Full text

Life Sciences, Genetics, Molecular Genetics +17

Characterization of Progressive Motor Deficits in Mice Transgenic for the Human Huntington’s Disease Mutation

Rebecca J. Carter, Lisa A. Lione, Trevor Humby et al. · Journal of Neuroscience · 1999 · 959 citations · Full text

Life Sciences, Neurology, Neuroscience +17

Huntington's Disease

Jean Stipe, Dorothy A. White, Eleanor Van Arsdale · AJN American Journal of Nursing · 1979 · 604 citations

Life Sciences, Neuroscience, Pharmacology +17

Behavioural abnormalities and selective neuronal loss in HD transgenic mice expressing mutated full-length HD cDNA

P. Hemachandra Reddy, Maya Williams, Vinod Charles et al. · Nature Genetics · 1998 · 398 citations

Life Sciences, Neurobiology, Neuroscience +14