Huntington's Disease

Abstract

ted by both sexes. Each child of an afflicted parent has a 50 percent chance of inheriting the disease. This risk continues uninterrupted from one generation to the next. Occasionally, a parent dies before the age when the symptoms characteristically appear, and this may give the impression, incorrectly, that Huntington's disease has skipped a generation(2). The age of onset of symptoms is extraordinarily inconsistent. Although most individuals first develop symptoms between the ages of 30 and 40 years, symptoms can occur between 20 and 60, a span of four decades. Rare cases have been