Conditional expression of mutated K-ras accelerates intestinal tumorigenesis in Msh2-deficient mice

Analysis of lung tumor initiation and progression using conditional expression of oncogenic <i>K-ras</i>

Erica L. Jackson, Nicholas A. Willis, Kim L. Mercer et al. · Genes & Development · 2001 · 2K citations · Full text

Medicine, Cancer Biology, Oncology +17

Somatic activation of the K-ras oncogene causes early onset lung cancer in mice

Leisa Johnson, Kim L. Mercer, Doron C. Greenbaum et al. · Nature · 2001 · 1.2K citations

Medicine, Molecular Genetics, Oncology +14

Kisten ras mutations in patients with colorectal cancer: the “RASCAL II” study.

David Cunningham, J. Oates, Joanne Young et al. · IRIS UNIMORE (University of Modena and Reggio Emilia) · 2001 · 890 citations · Full text

Medicine, Genetics, Oncology +12

Endogenous oncogenic K-rasG12D stimulates proliferation and widespread neoplastic and developmental defects

David A. Tuveson, Alice T. Shaw, Nicholas A. Willis et al. · Cancer Cell · 2004 · 816 citations · Full text

Medicine, Genetics, Oncology +14

Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination, and predisposition to cancer

Niels de Wind, Marleen Dekker, Anton Berns et al. · Cell · 1995 · 792 citations · Full text

Life Sciences, Genetics, Molecular Genetics +16