Inactivation of the mouse Msh2 gene results in mismatch repair deficiency, methylation tolerance, hyperrecombination, and predisposition to cancer

The human mutator gene homolog MSH2 and its association with hereditary nonpolyposis colon cancer

Richard Fishel, Mary Kay Lescoe, Manchanahalli R. Satyanarayana Rao et al. · Cell · 1993 · 2.9K citations

Life Sciences, Genetics, Oncology +14

Mutations of a mutS homolog in hereditary nonpolyposis colorectal cancer

Fredrick S. Leach, Nicholas C. Nicolaides, Nickolas Papadopoulos et al. · Cell · 1993 · 2.3K citations

Life Sciences, Genetics, Molecular Genetics +17

Mutation in the DNA mismatch repair gene homologue hMLH 1 is associated with hereditary non-polyposis colon cancer

Christian Bronner, Sean M. Baker, Paul T. Morrison et al. · Nature · 1994 · 2.1K citations

Life Sciences, Genetics, Molecular Genetics +12

Mutation of a <i>mutL</i> Homolog in Hereditary Colon Cancer

Nickolas Papadopoulos, Nicholas C. Nicolaides, Ying-Fei Wei et al. · Science · 1994 · 1.8K citations

Life Sciences, Genetics, Molecular Genetics +17

Mutations of two P/WS homologues in hereditary nonpolyposis colon cancer

Nicholas C. Nicolaides, Nickolas Papadopoulos, Bo Liu et al. · Nature · 1994 · 1.5K citations

Life Sciences, Genetics, Molecular Genetics +14