Concepedia

Mismatch Repair

Mismatch Repair is a DNA repair mechanism that corrects base-pair mismatches and small insertion-deletion loops arising during DNA replication by recognizing the mismatch, excising the incorrect nucleotide segment from the newly synthesized strand, and resynthesizing the correct sequence.

2.7K

Publications

208.4K

Citations

10.1K

Authors

2.1K

Institutions

Publications per year

2017–2026

415

Variants

Dna Mismatch RepairMmr

Parents

Children

Publications

2.7K

Nivolumab in patients with metastatic DNA mismatch repair-deficient or microsatellite instability-high colorectal cancer (CheckMate 142): an open-label, multicentre, phase 2 study

Michael J. Overman, Ray McDermott, Joseph L. Leach et al. · The Lancet Oncology · 2017 · 2.8K citations · Full text

, , +14

Mutation in the DNA mismatch repair gene homologue hMLH 1 is associated with hereditary non-polyposis colon cancer

Christian Bronner, Sean M. Baker, Paul T. Morrison et al. · Nature · 1994 · 2.1K citations

, , +12

Mutation of a <i>mutL</i> Homolog in Hereditary Colon Cancer

Nickolas Papadopoulos, Nicholas C. Nicolaides, Ying-Fei Wei et al. · Science · 1994 · 1.8K citations

, , +17

Defective Mismatch Repair As a Predictive Marker for Lack of Efficacy of Fluorouracil-Based Adjuvant Therapy in Colon Cancer

Daniel J. Sargent, Silvia Marsoni, Geneviève Monges et al. · Journal of Clinical Oncology · 2010 · 1.6K citations · Full text

, , +17

RAF/RAS oncogenes and mismatch-repair status

Harith Rajagopalan, Alberto Bardelli, Christoph Lengauer et al. · Nature · 2002 · 1.2K citations

, , +14

1–5 of 2.7K

Authors

10.1K

  1. PM
    Paul Modrich

    Duke Medical Center, United States

    75 publications · 14.2K citations

    59

    h-index

  2. TA
    Thomas A. Kunkel

    National Institute of Environmental Health Sciences, United States

    69 publications · 8.9K citations

    50

    h-index

  3. RD
    Richard D. Kolodner

    University of California San Diego, United States

    66 publications · 9.5K citations

    47

    h-index

  4. JJ
    Josef Jiricny

    University of Zurich, Switzerland

    60 publications · 5.9K citations

    38

    h-index

  5. EA
    Eric Alani

    Cornell University, United States

    44 publications · 3.8K citations

    35

    h-index

1–5 of 10.1K

Institutions

2.1K

  1. National Institute of Environmental Health Sciences

    Durham, United States

    59 h-index

    330 publications

    41.1K citations

  2. National Institutes of Health

    Bethesda, United States

    57 h-index

    336 publications

    37.9K citations

  3. Duke Medical Center

    Durham, United States

    57 h-index

    247 publications

    41.2K citations

  4. Howard Hughes Medical Institute

    Chevy Chase, United States

    55 h-index

    162 publications

    30.9K citations

  5. Duke University Hospital

    Durham, United States

    54 h-index

    230 publications

    37.5K citations

  6. University of North Carolina at Chapel Hill

    Chapel Hill, United States

    48 h-index

    222 publications

    21.1K citations

  7. University of California San Diego

    San Diego, United States

    46 h-index

    224 publications

    19.1K citations

  8. Harvard University

    Cambridge, United States

    41 h-index

    208 publications

    27K citations

1–8 of 2.1K

Venues

  1. Proceedings of the National Academy of Sciences

    PNAS · 187 publications · 22.1K citations

    87

    h-index

  2. Journal of Biological Chemistry

    JBC · 207 publications · 17.7K citations

    77

    h-index

  3. Nucleic Acids Research

    212 publications · 12.2K citations

    63

    h-index

  4. Molecular and Cellular Biology

    MCB · 91 publications · 8.3K citations

    54

    h-index

  5. Genetics

    143 publications · 8.4K citations

    51

    h-index

1–5