Concepedia

Publication | Closed Access

G-Quadruplex Ligand RHPS4 Potentiates the Antitumor Activity of Camptothecins in Preclinical Models of Solid Tumors

DOI

90

Citations

16

References

2008

Year

Carlo Leonetti, Marco Scarsella, Giuseppe Riggio, Angela Rizzo, Erica Salvati, Maurizio D’Incalci, Lidia Staszewsky, Roberta Frapolli, Malcolm F. G. Stevens, Antonella Stoppacciaro,
Clinical Cancer Research

Abstract

Our data show that RHPS4 has a good pharmacodynamic profile and in combination therapy produces a strong antitumoral activity, identifying this drug as promising agent for clinical development.

References

YearCitations

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