The human telomere terminal transferase enzyme is a ribonucleoprotein that synthesizes TTAGGG repeats

[57] Sequencing end-labeled DNA with base-specific chemical cleavages

Allan M. Maxam, Walter Gilbert · Methods in enzymology on CD-ROM/Methods in enzymology · 1980 · 14.7K citations

Pharmacy, Biotechnology, Molecular Biology +13

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

John David Dignam, Russell M. Lebovitz, R G Roeder · Nucleic Acids Research · 1983 · 11.6K citations · Full text

Life Sciences, Molecular Biology, Molecular Genetics +17

Identification of a specific telomere terminal transferase activity in tetrahymena extracts

Carol W. Greider, Elizabeth H. Blackburn · Cell · 1985 · 3.4K citations · Full text

Life Sciences, Biochemistry, Molecular Biology +11

A highly conserved repetitive DNA sequence, (TTAGGG)n, present at the telomeres of human chromosomes.

Robert K. Moyzis, Judy M. Buckingham, L. Scott Cram et al. · Proceedings of the National Academy of Sciences · 1988 · 2.4K citations · Full text

Life Sciences, Genetics, Molecular Genetics +16

A telomeric sequence in the RNA of Tetrahymena telomerase required for telomere repeat synthesis

Carol W. Greider, Elizabeth H. Blackburn · Nature · 1989 · 1.7K citations

Life Sciences, Genetics, Molecular Biology +13