Concepedia

Effect of Simvastatin/Ezetimibe 10/10 mg Versus Simvastatin 40 mg on Serum Vitamin D Levels

Evangelos Liberopoulos, Stefania Makariou, Elisavet Moutzouri, Michael S. Kostapanos, Anna Challa, Moses Elisaf

Journal of Cardiovascular Pharmacology and Therapeutics · 2013 · 22 citations · 13 references

DOI

Abstract

For similar LDL-C lowering simvastatin 40 mg is associated with greater increase in 25(OH)VitD compared to simvastatin/ezetimibe 10/10 mg. Whether this difference is relevant in terms of CVD risk reduction is unknown.

References

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A multicenter, randomized, double-blind, placebo-controlled, factorial design study to evaluate the lipid-altering efficacy and safety profile of the ezetimibe/simvastatin tablet compared with ezetimibe and simvastatin monotherapy in patients with primary hypercholesterolemia

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